Ostarine, otherwise known as enobosarm or MK-2866, is a selective androgen receptor modulator (SARM) that was initially developed as a means to combat muscle wastage and osteoporosis, by mimicking the effects of testosterone. Since its creation at the turn of the millennium by GTx Inc., ostarine has been used in a variety of clinical trials for conditions including post-menopausal tissue wastage, tissue wastage in lung and prostate cancer sufferers and even urinary incontinence.
The ostarine molecule (C19H14F3N3O3)
What interests us here, of course, is ostarine’s properties for healthy individuals seeking strength and fitness benefits.
So: can ostarine actually confer such benefits?
The answer is a very firm ‘yes’; but as with all the other SARMs in this series – ligandrol, RAD140, cardarine and andarine – ostarine has specific uses and will suit some more than others.

Ultimately, you must know who you are, and that includes whether you are male or female, and what you want to achieve, before deciding on which SARM to take. You must also be in no doubt of the potential risks and side effects, which we will discuss below.
Ostarine is often referred to as the ‘most anabolic’ SARM, and it’s for this reason that bodybuilders, strength athletes (powerlifters, Olympic lifters, strongmen), practitioners of contact sports, martial artists and gymbros are the ones you’ll find taking it.
All of these groups seek the following benefits:
- Loss of unwanted body fat
- Increased lean muscle mass (even in a caloric deficit)
- Increased energy levels

How to Buy Ostarine
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